植物有疫苗嗎 ? CRISPR/Cas systems

植物有疫苗嗎 ? 

CRISPR/Cas 系統目前正在研究中，但出生前要打了，透過基因轉殖的方式獲得免疫力。

Schematic representation of class 2 CRISPR/Cas systems to confer resistance to plant viruses. After plant viruses enter into plant cells, the viral genome is uncoated and transcribed, or translated with the help of host factors. Plant viruses then multiply their genome in the nucleus or in the cytoplasm. The viral genome DNA or RNA can be targeted, destroyed, or interfered with by CRISPR/Cas9 or CRISPR/Cas13 (or FnCas9) systems in the nucleus or in the cytoplasm, respectively, which inhibits viral infection. In addition, the mutation or deficiency in host susceptibility factors edited by the CRISPR/Cas9 system also perturbs viral infection. However, some new viral variants might be generated as by-products when CRISPR/Cas systems edit the viral genome, which might drive the risk of viral evolution.

CRISPR/Cas systems versus plant viruses: engineering plant immunity and beyond (Ali and Mahfouz 2021)

資料來源:

https://www.researchgate.net/publication/345314858_Control_of_Plant_Viruses_by_CRISPRCas_System-Mediated_Adaptive_Immunity

https://academic.oup.com/plphys/advance-article-abstract/doi/10.1093/plphys/kiab220/6274908?redirectedFrom=fulltext